Acetaminophen Oral Suspension Calculator

Calculate Amounts

Enter the total volume (mL): Enter the concentration (mg/mL): Calculate

Results

Formula

Acetaminophen (micronized): 32 mg/mL

Sucrose syrup: 40% w/w

Sodium benzoate: 0.1% w/w

Xanthan gum: 0.2% w/w

Glycerin: 5% w/w

Sorbitol solution (70%): 10% w/w

Sodium saccharin: 0.1% w/w

Flavor (mint): 0.01% w/w

Purified water: q.s. to 100%

Preparation Steps

1. Prepare sucrose syrup containing sodium benzoate and cool to 30°C.
2. Disperse xanthan gum in glycerin.
3. Add the xanthan gum dispersion to the sucrose syrup and mix thoroughly.
4. In a separate container, mix sorbitol solution, sodium saccharin, and flavor.
5. Combine the mixtures from steps 3 and 4.
6. Add micronized acetaminophen to the combined mixture and homogenize.
7. Add purified water to achieve the final volume and mix well.

Storage and Stability

Store in a tightly closed, light-resistant container. Shake well before use. Stable for up to 24 months when stored at room temperature.